References - Arraystar tRNA | tRNA Research Literature

Overview

Primary literature supporting Arraystar tRNA technologies

This reference list gathers key publications cited by Arraystar for tRNA research, covering tRNA expression and isoacceptor biology, translation regulation, tRNA charging and aminoacyl-tRNA synthetases, tRNA modifications, and tRNA-derived fragments in disease.

Each reference includes its PubMed identifier (PMID) so you can verify the citation and access the original study. The list is maintained alongside the Arraystar tRNA product and service pages.

Why are these references important?

These references document the scientific basis of Arraystar tRNA technologies, including why tRNA abundance, charging, and modification matter for translation and disease. They help researchers design experiments and interpret tRNA and tRF/tiRNA profiling results.

Reference List

References cited by Arraystar tRNA services and products

Gingold H, et al. (2014). A dual program for translation regulation in cellular proliferation and differentiation. Cell 158, 1281-92. PMID: 25215487
Pavon-Eternod M, et al. (2013). Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. RNA 19, 461-6. PMID: 23431330
Mei Y, et al. (2010). Apoptotic regulation and tRNA. Protein Cell 1, 795-801. PMID: 21113408
Berns A (2008). A tRNA with oncogenic capacity. Cell 133, 29-30. PMID: 18394985
Waldman YY, et al. (2009). TP53 cancerous mutations exhibit selection for translation efficiency. Cancer Res 69, 8807-13. PMID: 19887606
Kushner JP, et al. (1976). Elevated methionine-tRNA synthetase activity in human colon cancer. Proc Soc Exp Biol Med 153, 273-6. PMID: 995958
Marshall L, et al. (2008). Elevated tRNA(iMet) synthesis can drive cell proliferation and oncogenic transformation. Cell 133, 78-89. PMID: 18394991
Pavon-Eternod M, et al. (2009). tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Res 37, 7268-80. PMID: 19783824
Zhou Y, et al. (2009). High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma. Biochem Biophys Res Commun 385, 160-4. PMID: 19450555
Begley U, et al. (2013). A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-alpha. EMBO Mol Med 5, 366-83. PMID: 23381944
Goodarzi H, et al. (2016). Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression. Cell 165, 1416-27. PMID: 27259150
Krokowski D, et al. (2013). A self-defeating anabolic program leads to beta-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux. J Biol Chem 288, 17202-13. PMID: 23645676
Girstmair H, et al. (2013). Depletion of cognate charged transfer RNA causes translational frameshifting within the expanded CAG stretch in huntingtin. Cell Rep 3, 148-59. PMID: 23352662
van Weringh A, et al. (2011). HIV-1 modulates the tRNA pool to improve translation efficiency. Mol Biol Evol 28, 1827-34. PMID: 21216840

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Expert-written reviews on tRNA biology, modifications, charging, and platform selection.

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Client publications of Arraystar technologies, grouped by service and product.

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FAQ

Common questions about Arraystar tRNA references

How are these references selected?

References are curated by Arraystar scientists to support the tRNA technologies offered in this portal, covering tRNA expression, isoacceptors and isodecoders, translation regulation, tRNA charging, modifications, and tRNA-derived fragments. Each entry is a peer-reviewed primary study with a PubMed identifier for verification.

Can I access the full papers?

Each reference includes a PubMed identifier that links to the National Library of Medicine record for the paper. From PubMed you can access the abstract, citation details, and, for open-access articles, the full text. Contact us if you need help locating a specific study.

Do these references cover tRNA modifications?

Yes. Several references cover tRNA modification biology, including tRNA methyltransferases, m7G and m3C modification, and the role of modified tRNAs in translation and disease. These studies support Arraystar tRNA modification sequencing services such as TRAC-Seq, HAC-Seq, and LC-MS based analysis of modifications.

How do references relate to Arraystar services?

The references document the biology behind Arraystar tRNA services and products, including tRNA sequencing, tRNA PCR arrays, pretreatment kits, and modification analysis. They help you design experiments and interpret results, and they are cited in the service pages of this portal.

Are references updated regularly?

The reference list is maintained alongside Arraystar tRNA services and is reviewed as new tRNA, tRF and tiRNA studies are published. Featured client publications are listed separately on the Publications page, which is updated as new papers appear in high-impact journals.

How can I cite these references in my work?

Each entry includes the author, year, journal, and PubMed identifier needed for citation. We recommend citing the original paper using the journal citation format required by your target publication, and mentioning the Arraystar service or product used in your study.