Mass Spectrometry (LC-MS)

LC-MS Based RNA Modification Analysis Service – Selected/Isolated RNA

Arraystar LC-MS RNA Modification Analysis Service analyzes 55 nucleoside modifications and characterizes global modification profile of any RNA class you selected or isolated.

Benefits

• Quantitative analysis of complex RNA modifications from RNA samples.
• Full service sample-to-data – From nucleoside analyte preparation, LC-MS/MS data acquisition, analysis to report.
• High Performance – Highly optimized experimental procedures, state-of-the-art LC-MS system, expertise in operation.
• Best analytical coverage – Simultaneous profiling of 55 nucleoside modifications in RNA.

Service Order Guide

1. Check if your modifications of interest are in our standard detection list.
2. Read our RNA Submission Guide to make sure your samples are qualified for submission.
3. Click “Add To Cart” below and make your payment online.
4. Fill out the Project Information Sheet and send your samples to Arraystar following the Online Ordering Directions for LC-MS Services.

* We offer bulk order pricing, $280/sample for 1-2 test, $270/sample for 3-10 tests, $260/sample for 11-20 tests, $250/sample for 21-30 tests, $240/sample for 31-50 tests, and $230/sample for >50 tests.

Service NameCatalog NoSizePrice
LC-MS Based RNA Modification Analysis Service - Selected/Isolated RNAAS-LC-R-S1 sample

Table1. Nucleoside modifications profiled by Arraystar LC-MS mRNA Modification Analysis

NumberNucleosideSymbolNumberNucleosideSymbol
13′-O-methyladenosine3′-OMeA23′-O-methyluridine3′-OMeU
32′-O-methylcytidineCm45-methyl-2-thiouridinem5s2U
53-methylcytidinem3C65-methoxyuridinemo5U
75-methylcytidinem5C8pseudouridine
9N6-isopentenyladenosinei6A102′-O-methylinosineIm
115,2′-O-dimethylcytidinem5Cm123-methyluridinem3U
131-methyladenosinem1A141-methylpseudouridinem1
152-thiocytidines2C165-hydroxymethylcytidinehm5C
17N2, N2, 7-trimethylguanosinem2,2,7G185,2′-O-dimethyluridinem5Um
19N4-acetyl-2′-O-methylcytidineac4Cm20N6-threonylcarbamoyladenosinet6A
21N6-methyladenosinem6A222-methylthio-N6-threonylcarbamoyladenosinems2t6A
233′-O-methylcytidine3′-OmeC245-carboxymethyluridinecm5U
252′-O-methyladenosineAm265-methoxycarbonylmethyl-2-thiouridinemcm5s2U
27N2, N2-dimethylguanosinem22G285-Methoxycarbonylmethyluridinemcm5U
295′-O-methylthymidine5′-OMeT302-methylthio-N6-isopentenyladenosinems2i6A
312′-O-methyluridineUm32Peroxywybutosineo2w
33inosineI345-taurinomethyl-2-thiouridinetm5s2U
352′-O-methylguanosineGm365-oxyacetic acid uridinecmo5U
371-methylguanosinem1G385-carbamoylmethyuridinencm5U
397-methylguanosinem7G40QueuosineQ
41N2-methylguanosinm2G425-taurinomethyluridinetm5U
433′-O-methylinosine3′-OMeI445-formyl-2′-O-methylcytidinef5Cm
452-thiouridines2U46dihydrouridineD
474-thiouridines4U485-formylcytidinef5c
495-methyluridinem5U50wybutosineW
51N4-acetylcytidineac4C525-methoxycarbonylmethyl-2′-o-methyluridinemcm5Um
53N6, O2′-methyladenosinem6Am545-methylaminomethyl-2-thiouridinemnm5s2U
555-hydroxyuridineho5U