In traditional gene expression profiling experiments, RNA labeling is typically initiated by oligo-dT-primed reverse transcription, which cannot generate Cy3- or Cy5-labeled antisense RNAs along the entire length of the transcript without 3′ bias. Furthermore, this labeling method excludes a significant fraction (>25%) of RNA molecules that lack a classical poly(A) tail [1, 2]. To solve […]
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Comprehensive & Reliable Collection • Arraystar’s LncRNA Arrays are designed using our comprehensive and reliable Long non-coding RNAs database, which integrates the lncRNAs carefully collected from the most authoritative databases, such as Refseq, UCSC known genes, Ensembl and many relative literatures. Most importantly, our database is continually updated to ensure that all the latest annotated LncRNAs are being covered.
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circular RNA expression profiling by RNA-seq faces major numerical and practical challenges. Numerically, circular RNAs as a population are typically present at much lower abundance levels, at about 5~10% of linear RNAs (Fig. 1A). The cross circular junction sequences necessary for circular RNA identification are even lower as a fraction of the full length transcripts
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Introduction Circular RNA (circRNA) is a novel type of RNA that, unlike linear RNA, forms a covalently closed continuous loop, and is highly represented in the eukaryotic transcriptome. Most of these circRNAs are generated from exonic sequences, are conserved across species, and often show tissue/developmental-stage-specific expression. Circular RNAs are more stable than linear RNAs owing
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UCRs and Their Function T-UCR Expression Patterns in Cancer The Updated Annotation of the 481 UCRs The Relationship between T-UCRs and Cancer Probe Design Strategy of the Arraystar Human T-UCR Array
What are DoG RNAs? Downstream-of-gene (DoG) RNAs are RNA transcripts that arise downstream of ~10% of host genes and are continuous with their upstream RNAs [1]. DoGs are defined as having a minimal length of 5 kb beyond the polyadenylation signal (PAS) at transcription end site (TES), with maximal length up to 200 kb in
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