Webinars Archives

How to Profile Small RNA Modifications?

This webinar covers:
• Small RNA modifications in biological functions and diseases
• Small RNA modifications as biomarkers
• Challenges of small RNA modification profiling
• Solution to small RNA modification profiling with microarrays

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m6A Profiling at Single Nucleotide Resolution

Arraystar m6A Single Nucleotide Arrays uses methyl-sensitive MazF RNase to precisely locate the m6A site and microarray for ultrasensitive detection.

The webinar covers:
1) The roles of m6A sites in human cancers and diseases;
2) How to best profile and study m6A sites.​

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Quantify the percentage of modification at transcript level

Current transcriptome-wide RNA modification profiling methods deal mostly with mapping the modification sites but are unable to achieve modification stoichiometry. The lack of such quantitative information has been a major concern for scientists. This video presents how Arraystar Epitranscriptomic two-color channel microarrays quantify the percentage of RNA that is modified for each transcript isoform.

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The only practical choice for circular RNA profiling

Circular RNAs (circRNA) are resistant to exonuclease degradation and some can be present at abundant yet cell type specific levels. Many circRNAs harbor multiple microRNA binding sites to function as microRNA sponges in gene regulation. Their unique properties poses special profiling challenges. We will discuss the best practical circRNA profiling solutions and share the success stories.

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Super-enhancer lncRNAs – The master regulators

Super-enhancers are top ranking master gene regulators that program the cell lineages, types, identities, and diseases. Super-enhancer lncRNAs (SE-lncRNA) transcribed from the super-enhancers activate the target coding genes by multiple mechanisms. Arraystar SE-lncRNA microarrays simultaneously profile SE-lncRNAs and their target genes, with high sensitivity, unambiguous isoform detection, comprehensive annotations and transcript-specific level accuracy.

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