Circular RNAs (circRNAs) are no longer just scientific curiosities—they are emerging as crucial players in disease diagnostics and therapy development. Once dismissed as splicing anomalies, circRNAs are now recognized for their potential in combating cancer, cardiovascular diseases, and Alzheimer's.

Highlighted in a recent Nature article [1], Dr. Yanggu Shi, Senior Scientist at Arraystar, discusses the transformative power of circRNA microarray technology. Designed to detect these elusive RNA molecules, Arraystar's innovative solutions enable researchers to decode circRNA functions with unparalleled accuracy.

Fig 1. Potential functions of circular RNA[1]

Why circRNAs Matter:

• Unique molecular loops with diverse cellular roles.
• Powerful biomarkers for disease detection.
• Promising candidates for therapeutic innovations.

The article emphasizes both the excitement and difficulty in studying circRNAs, highlighting the expanding toolbox and the "terra incognita" (Latin for 'unknown land') nature of the field, which continues to hold immense potential for discovery.

How CircRNA Microarrays Accelerate Discovery: Our circRNA microarrays pinpoint critical circular junctions, providing precise and reproducible results for human, mouse, and rat samples. This technology empowers researchers to unlock the secrets of circRNAs with ease.

Discover how circRNA research is opening new frontiers in biology and medicine. Read the full Nature article to learn more.
For more on our circRNA solutions, visit Arraystar.com or contact us directly.

• Epitranscriptomic Array
   [PMID: 38355624] Xiong YW, et al.
   (2024) Nature Communications

• Small RNA Modification Array
   [PMID: 38747146] Zhang J, et al.
   (2024) Circulation Research

• Circular RNA Array
   [PMID: 39695693] Hu Y, et al.
   (2024) Molecular Cancer

• tRNA Sequencing
   [PMID: 38519786] Wu X, et al.
   (2024) Nature Cancer

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Valid 06/01/2025 - 08/31/2025