Publications |  Promo  
Over 20% OFF RNA Modification Seq and Microarray Service

m6A/m5C/m1A/ac4C/m7G/Ψ

In addition to m6A as the most studied prominent internal epitranscriptomic modification in mRNAs and lncRNAs, other epitranscriptomic modifications, such as m1A, m5C, ac4C, m7G, and Ψ, have been increasingly discovered to play novel biological or clinical roles. These RNA modifications can modulate mRNA translation, alternative splicing, nuclear export and stability; affect RNA secondary structures and protein-RNA interactions; and regulate DNA repair. They are also involved in diverse cancers, viral infections, and pathogen infection-induced myelopoiesis.

Arraystar offers both epitranscriptomic microarray and sequencing services for m6A/ m5C/m1A/ac4C/m7G/Ψ modifications. The comparison chart below can help you choose the most appropriate tool for your research purpose.

Epitranscriptomic Sequencing Epitranscriptomic Array
Total RNA amount
120 ug
5 ug
Research applications • Modification abundance for each peak.
• Not for %modification stoichiometry (%modification).
•Site location resolution ~100 nt.
• Primarily for mRNAs.
• For any species		 • Modification abundance for each transcript.
• %modification for each transcript.
• Specific for transcript isoforms.
• For modifications anywhere in whole transcripts;Known cataloged sites are annotated in dataset.
• Cover mRNAs, lncRNAs, and midsized ncRNAs simultaneously, or circular RNAs.
• For human, mouse, or rat species.
Performance • Less sensitive for low level RNAs
• Higher noise and false positives.
• Lower quantification accuracy.		 • Sensitive even for low level RNAs.
• Higher quantification accuracy.
qPCR validation Multiple MeRIP-qPCR amplicons to cover potential sites in a modification peak. Multiple MeRIP-qPCR amplicons to cover potential sites in a transcript.

 
Request Quote Now!
 
Request Quote Now!
 

Notes:
1. Offer valid through 3/31/2025. May not be combined with any other promotions or discounts.
2. Sample requirement: sufficient total RNA in good quality, minimum 6 samples.
3. Offer only valid for direct purchase from Arraystar Inc.



Selected Publications

• Epitranscriptomic Array
   [PMID: 38355624] Xiong YW, et al.
   (2024) Nature Communications

• Small RNA Modification Array
   [PMID: 38747146] Zhang J, et al.
   (2024) Circulation Research

• Circular RNA Array
   [PMID: 39695693] Hu Y, et al.
   (2024) Molecular Cancer

• tRNA Sequencing
   [PMID: 38519786] Wu X, et al.
   (2024) Nature Cancer

New Services

GlycoRNA Array Service

Cover Y-RNA/Y-RNA fragment, tRNA,
tiRNA&tRF, pre-miRNA, miRNA & more!

Request Quote

DoG RNA Array Service
Profile downstream-of-gene transcripts & all their target types simultaneously

Request Quote

Bioinformatics Analysis Service
For Ribo-Seq, Cut & Tag Seq, ATAC-Seq
& ChIP-Seq

Request Quote

 Promotions

20% OFF DRIPc-Sequencing!
- Exploring R-loop Regulation

Save Now!

Valid through 5/31/2025

Over 20% OFF RNA Modification
Services!

Epitranscriptomic Microarray

Save Now!

RNA Modification Sequencing

Save Now!

Valid through 3/31/2025
 
 
Arraystar Inc. 9430 Key West Avenue #128 Rockville MD 20850 www.arraystar.com
Email: info@arraystar.com Phone: 888-416-6343; 240-314-0388